Accelerating the development of cell-based products with denovoMATRIX Services.

YOUR CHALLENGE

You are developing a new cell-based product with multiple key areas to focus on. You are working towards approaching deadlines, and are looking to leverage external support. Specifically, you want to optimize the microenvironment of your cells of interest to enhance attachment, proliferation and performance, while maintaining cell quality. You need experts that help you develop, optimize and characterize your cell product to save time.

OUR SOLUTION

A highly-qualified team with in-depth experience in cell characterization and biomaterial development. Our experts will support your team to drive your product development and cell manufacturing processes to completion. We tailor service projects to individual requirements, ensure open communication and high-quality results.

YOUR BENEFITS

  • Acceleration – expand the development capacities of your cell-based product.

  • Validation – independent verification of your cells and processes.

  • High quality – established processes and qualified professionals ensure reliable results.

Assisting with cell characterization and biomaterial development for your upscale.

Cell characterization

Confirming cell identity, fidelity and functionality is paramount for the development of a safe and consistent cell-based product. Our phenotypic, genetic and functional assessments of your cells of interest can be requested as stand-alone service or included in a biomaterial development project. Our cell characterization services include but are not limited to:

  • Evaluation of growth kinetics and viability
  • Analysis of differentiation potential
  • Characterization of cell surface antigen expression
  • Assessment of genetic fidelity on chromosomal and sub-chromosomal level

Biomaterial development & manufacturing

Anchorage-dependent cells require interactions with a substrate for cell survival and active proliferation. In vivo, this is provided by diverse structural proteins in the extracellular matrix. In vitro, our biomaterials can functionally recreate the natural microenvironment of your cells of interest and improve cell attachment, proliferation as well as performance. Our biomaterial development services include but are not limited to:

  • screenMATRIX staining, high throughput imaging and analysis
  • biomaterial candidate selection and custom-format/scaffold coating
  • characterization of coated scaffold materials
  • out-licensing of coating compositions

LET US DO THE HEAVY LIFTING.

We develop, characterize and manufacture extracellular matrix-mimetic coatings for your applications. denovoMATRIX also offers its expertise in cell line establishment, cell expansion and cell analysis to enhance your research and development projects. Contact us for more information on our service and licensing offer.