Enabling Biology in vitro.
denovoMATRIX provides tools for cell manufacturing in higher quality, quantity and safety.
SUPPORTING OUR CUSTOMERS
We were searching for chemical-defined coatings that could increase the adhesion of different cell types on our bio-chips. With the screenMATRIX, we were able to test different surfaces and we could find coats that fit all the cell types we were working with.
denovoMATRIX is an ideal partner for us because of the technical capabilities they bring to this partnership. The feedback we receive from them will help ensure that our products are achieving the desired results, while being user-friendly for our customers.
In Mesenchymal stromal cell isolation and expansion, it is very important to have standardized protocols, due to the high natural variability present in donors as well as the biology of this particular cell type. Standardization of the cell culture conditions is essential – for that reason, we’ve gotten in touch with denovoMATRIX. In our collaboration we have been able to identify multiple cell culture conditions where cell grow better and establish standardized protocols for isolation/expansion. We absolutely believe that denovoMATRIX is a great source for standardized MSC lines.
We are very excited to combine our expertise in cell culture engineering and process development to provide guidance to the industry and look forward to sharing the results of our iPSC study in the coming months.
denovoMATRIX is an innovation leader known for its technology that enables large-scale cell manufacturing. Our collaboration positions us well to serve patients from clinical trials to commercial production.
We tested the denovoMATRIX product myMATRIX MSC. At the end of the cell expansion, we collected more cells with the myMATRIX MSC (around 20%) than in the controls.
We see significant potential for denovoMATRIX’ technology to improve yield and performance in cell and gene therapy applications and enable the next generation of cell culture solutions.
I would recommend denovoMATRIX biomaterials to anyone who is aiming to significantly improve the growth and function of their human stem cells in vitro.
REDEFINING CELL CULTURE IN LIFE SCIENCE
OUR PRODUCT LINES
Expand mesenchymal stromal cells in serum-free conditions with myMATRIX MSC
Working in serum-free or even chemically defined conditions for mesenchymal stromal cell (MSC) culture? myMATRIX MSC provides a chemically defined cell adhesion-promoting microenvironment offered as pre-coated cultureware, specially formulated for expansion of human MSC in serum-free and xeno-free media.
Culture induced pluripotent stem cells in chemically defined processes with myMATRIX iPSC
Need chemically defined substrates in your induced pluripotent stem cells (iPSC) processes? myMATRIX iPSC offers a synthetic cell culture substrate in a ready-to-use format supporting long-term expansion of iPSC. myMATRIX iPSC fulfills the requirements needed for translational and upscale applications while being suitable for a wide variety of cell culture routines.
Transfer your stem cells to industry scale with beadMATRIX
Your proof-of-concept is complete and you are ready to think in larger scale? beadMATRIX microcarriers have been developed for simple transfer of cell expansion from lab-scale to industry standards while maintaining the proven composition, performance, and safety profile. beadMATRIX supports a variety of stem cells including Mesenchymal Stromal Cells and induced Pluripotent Stem Cells.
OUR SERVICES
Find the perfect coating for YOUR cells with screenSERVICE
Searching for the ideal microenvironment for your application? Choosing our screenSERVICE is the most efficient approach to your customized coating. We support you to test a large variety of factors for isolating, maintaining or differentiating your cells by providing our biomaterial library in format our screenMATRIX and assist in candidate selection. By this, we give you our most powerful tools and share our expertise towards cell specific culture, serum-free.
LET US DO THE HEAVY LIFTING.
We develop, characterize and manufacture extracellular matrix-mimetic coatings for your applications. denovoMATRIX also offers its expertise in cell line establishment, cell expansion and cell analysis to enhance your research and development projects. Contact us for more information on our service offer.
OUR STORY
Why
The natural environment of cells is a complex network of proteins and polysaccharides and defines the nature of the resident cells. This unique niche can be recapitulated by biomaterials. Biologically relevant biomaterials can maintain the identity and function of cells isolated from tissue in industrial processes.
How
The denovoMATRIX biomaterial technology can reliably recreate key functional aspects of the cellular environment for optimal cell growth and performance in vitro. Through the use of chemically defined components, we bring value to our customers in translational research and industrial cell manufacturing.
